Why It Could Actually Work:
Now, what I said earlier about the gremlins and Audrey II being "supernatural" threats to humanity? That's not entirely accurate, because both monsters are in fact aliens.
We know as much about Audrey II thanks to the song "Mean Green Mother from Outer Space," which reveals the plant's origin as an alien species "from past the stars and beyond the moon." As for Gremlins, the official novelization of the movie explains that the mogwai were originally created on the planet Enz by an alien scientist called Mogturmen, who easily could also have been the creator of Audrey II.
Consider how the aliens only turn homicidal due to their diet. With the mogwai, it was eating after midnight. With Audrey II, it was feeding on human blood. I don't know much about biology, but I'm guessing that producing murder instead of gas due to something you ate isn't a very useful evolutionary trait, and would make more sense as the result of a genetic experiment gone horribly wrong. The Gremlins novel tells us that the mogwais transforming into gremlins was a mistake on Mogturmen's part, so we know he isn't that good of a scientist. This makes him exactly the type of guy who would also try to create a sentient plant with a mouth for reasons we probably shouldn't get into.
Unnecessary censorship ruins your childhood once again!
It's also important to note that Gizmo (the first mogwai) and Audrey II were both sold to their movie's protagonist by walking illustrations from The 1800s Encyclopedia of Oriental Races:
Of course one of them is named Chang!