The only way that USB drive could be more obnoxious is if it were full of bootleg Dane Cook routines.
It's basically like having a particularly malicious virus, so really you can achieve the same result by taking a regular USB drive to a public library computer and then lending it to a friend. Presumably this was created by someone who went through a devastating malware attack and thought "Hilarious!"
"More people need to go through this, for no good reason."
The available "pranks" include jerking the cursor around, turning caps lock on and off indiscriminately and typing nonsensical snippets of text at random times, essentially recreating the experience of being 14 and on MySpace all over again. You can control the frequency with which these things happen through a series of buttons on the device itself, which also features a convenient time delay setting so that it doesn't start working immediately after you volunteered to clean the 10 years of dust off the back of your friend's desktop computer.