When Johnny Depp got the role of Willy Wonka, he decided to base his performance on what he imagined George W. Bush acted like while high on drugs. More on that and 29 other bizarre inspirations behind famous movies and shows: 

The Scooby Gang was based on the characters in a 1960s TV show. It was called The Many Loves of Dobie Gillis, and it was a teen sitcom that the creators of Scooby-Doo basically just lifted the main characters from. CRACKED.COM


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