Well, a gamer who goes by the handle Bearzly decided to use one of these specialized peripherals to play Dark Souls, one of the most difficult games of all time. It's a brutal experience in which any minutely wrong movement can send you hurtling off a cliff or impale you on an enemy spear, causing you to lose hours of progress. So Bearzly decided that he should play it with a fucking Guitar Hero guitar.
If you're not familiar, guitars are not designed to maneuver a swordsman through terrifying nightmares. One of the buttons on a Guitar Hero controller is a whammy bar, and another is a nubby little flagellum made for strumming. So even after cleverly remapping all the buttons, he couldn't move his character to the left. He also couldn't block heavy attacks, move the camera to the right, or understand the difference between a challenge and simple masochism.
The lack of Star Power wasn't doing him any favors, either.
Most people who play Dark Souls with a regular controller give up after several hundred deaths, and this guy beat it with a character who was barely listening to him. Playing Dark Souls with a Guitar Hero guitar is like teaching an actual person to fight skeletons using only an electric guitar for communication and holy shit we just came up with the sweetest idea for a kung fu movie ever.