Basically, it's nature's complicated "the triangle doesn't go in the square hole" law, with a bunch of subset rules that will kill off your children if you decide to take a hammer to the triangle. Meaning that as that species further evolves, there is no possible chance for you to create a new species closer to your own that you could stand to look at for five minutes.
Of course, that's assuming that you're even safe walking around among the members of this new freak species. Will they treat you like a novelty and cast you in hilarious insurance commercials, like the Geico cavemen? Or will they do to you what current humans would do if they finally caught Sasquatch roaming around through the forests (that is, stick you in a zoo)? Though whatever the freak-species decides to do with you won't be as bad as no sex for the rest of your life. Who knows, maybe someone will decide to make you the donkey in their next show.
And it's probably irrelevant, since your inability to make friends with mortals will go out the window long before then...