The Meanest, Dirtiest and Most Offensive Jokes Gilbert Gottfried Ever Told at a Comedy Central Roast

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12 People Who Retaliated Against Minor Slights in Petty and Over-the-Top Ways

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12 of the Most Brutal Deaths in Sitcom History

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‘Scrubs’ Creator Bill Lawrence Threatens That Reunion Movie Is ‘Inevitable’

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Iconic Comedy Duos That Could Give the Disgusting Brothers from 'Succession' a Run for Their Money

If only Logan Roy's security cams could capture some of this action.

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23 Horrifying Diseases You Won't Believe Existed

By:: AM Smiley

October 11, 2014

We watch a show like House and chalk the implausibility of its patients' maladies up to sensationalism for the sake of entertainment. But how implausible is it really?

With the help of esteemed image manipulator AuntieMeme, we present to you a boatload of crazy-sounding diseases ... that are absolutely real.

23 Entry by AM Smiley

Guinea Worm Disease Guinea Worms are parasitic Creative roundworms that are spread through Getty dirty water. People drink water Photo containing flea

22 Entry by AM Smiley

Vampire Syndrome Approximately one in a million people have Xeroderma Pigmentosum, which makes them extremely rlrrhwe sensitive to UV rays. These peop

21 Entry by AM Smiley

Stone Man Syndrome Fibrodysplasia Ossificans Progressiva (FOP) is a disorder in which muscle tissue, tendons, and ligaments gradually turn to bone. It

20 Entry by AM Smiley

Waterhouse- Friderichsen Syndrome Neisseria Meningitidis floods your body with bacteria, causing every organ system to fail. Creative Within a few hou

19 Entry by AM Smiley

Tree Man Syndrome What appears to be tree bark growing out of someone's. skin may actually be Epidermodysplasia Verruciformis Basically, they're a cov

18 Entry by AM Smiley

Sweating Sickness Sweating Sickness begins with a sense of apprehension, followed by violent cold shivers, headaches, severe neck, shoulder, and lim

17 Entry by AM Smiley

Werewolf Syndrome In the past, people with Congenital Hypertrichosis Lanuginosa (CHL)) were major sideshow attractions. Most famously, Fedor Jeftichew

16 Entry by AM Smiley

Elephantiasis Elephantiasis is a lymphatic obstruction that causes extreme swelling of skin and tissues, typically in the legs or testicles. Over 40 m

15 Entry by AM Smiley

Toothpick Fish The Candiru is a tiny fish with a reputation for invading and parasitizing the human urethra. Reports of urethral, uh, invasion date ba

14 Entry by AM Smiley

Jumping Frenchmen of Maine In 1878, George Miller Beard noticed that a lot of the French Canadian lumberjacks in Maine were jumping and screaming at t

13 Entry by AM Smiley

Water Allergy Despite the high water content in the human body, some people are allergic to water. Though it isn't a true allergy because it doesn't t

12 Entry by AM Smiley

Wool Sorter's Disease People who work with sheep are vulnerable to a pulmonary form of anthrax that comes from inhaling spores found in wool. It start

11 Entry by AM Smiley

Rose-Gardener's Disease Roses are a source of Sporothrix Schenckii, a fungus that can kill you. If it enters through small cuts and abrasions, like Cr

10 Entry by AM Smiley

Sleepy Sickness An epidemic of Encephalitis Lethargica swept the world in 1915. The disease attacks the brain, leaving some victims in a perpetual sta

9 Entry by AM Smiley

River Blindness Blindness is actually the less-diabolical result of Onchocerciasis. Onchocerca Volvulus (a blackfly found near rivers) injects you wit

8 Entry by AM Smiley

Porphyria oo2 00C It's speculated that porphyria is at least partially responsible for the vampire legend. Sufferers' gums recede to give the appearan

7 Entry by AM Smiley

Horn Player's Palsy Playing the horn can result in weakening and contraction of the facial muscles. Then the nerves become inflamed, leading to facial

6 Entry by AM Smiley

Butcher's Warts Butchers are subject to their own special malady, which are a variation of the Human Papillomavirus. Modern medicine is still not sure

5 Entry by AM Smiley

Mucocutaneous Leishmaniasis Mucocutaneous Leishmaniasis makes your face cave in. It's spread when a sand fly bites you, then poops in the wound. The r

4 Entry by AM Smiley

Dancing Plague In 1518, in Strasbourg, France, Frau Troffea started dancing in the street. After six days, others began to join in; after a week there

3 Entry by AM Smiley

Cotard's Delusion Cotard's Delusion is arare mental disorder in which a person sincerely believes he or she is missing body partssuch as the brain- or

2 Entry by AM Smiley

Alien Hand Syndrome People with Alien Hand Syndrome have a rogue hand that acts involuntarily, grasping objects or moving in a way contrary to what th

1 Entry by AM Smiley

Bagpiper's Fungus People who play bagpipes are prone to fungal lung infections and distended stomachs. Bagpipe skins are traditionally D cured with gl

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