Imagine the absolute worst moment of your life -- when you were in that terrible car accident, the day your fiance dumped you, that time you saw your parents having sex -- then magnify it by 10. Then imagine your eyes are being held open, a la A Clockwork Orange, while that moment is replayed in front of you over and over, forever. Also, it was your former best friend who did it to you. Hard to believe the entire thing could've been avoided by a careful viewing of Back to the Future II.
Mister Fantastic Turns POWs into COWs
If hopelessly f*****g up a space mission and walking away with superpowers and being adored by millions will foster a healthy ego, Reed Richards is the kind of rich genius who looked at that ego and said, "Yes, I'll have some of that, please. A little more. You know what, just leave the bottle." When the high that comes from having people call you "Mister Fantastic" with a straight face wears off, you've got to do something to replace it, and alien invasion + bored genius = opportunity! That was the case early in the Fantastic Four's career, when they successfully repelled a race of alien shape-changers called the Skrulls but were left with three captives. Noting that "no jail could hold them," Reed's solution was to force his prisoners to take the form of cows, then hypnotize them and ship them off to a random farm in upstate New York.
Fantastic Four #2
Where they excelled at shitting and blank stares.