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Serial killers in movies are all constrained by the same limitation: The imagination of a screenwriter, who is presumably not a murderous psychopath. No matter how disgusting or outright evil the fictional killer, there's somebody out there topping them in real life.
Some of our favorite pop culture series have their joy forcefully ripped from them whenever they face the harsh light of arithmetic.
Amidst all the moral lessons and dubious historical accounts, the Bible is chock full of examples of God just messing with people.