Everyone has to move sometime, and even if you don't, you probably are going to go on Craigslist and buy a TV or a couch or a caged bear sometime, and have to pick it up. Sooner or later, you are going to reach the limit of what you can carry in the trunk with the backseats folded down.
That's where the friend with the pickup truck comes in. You can take that IKEA box or bear cage that you've been unsuccessfully trying to stuff in your Civic for the past hour and just toss it in their truckbed.
This is a friendship you really have to be careful with, though. Pickup truck owners in circles of friends who mostly don't have pickup trucks usually tend to feel a little used, especially if they have trouble saying no. If you spot a look of terror in their eyes when you ask, "Hey, you have a pickup truck, don't you?" you might want to step lightly.