Together, they formed the AAAAARGHHH-Men.
Clendenen found isolated cases of patients reporting the same resistance, but nobody knew why it happened or how to remedy it. That doesn't mean there aren't theories, though. Some scientists in London were running a clinic for patients with Ehlers-Danlos Syndrome (a collection of rare genetic conditions making joints hyper-mobile) when they noticed that a lot of them were also immune to anesthesia. They have some ideas about how the EDS patients' slightly abnormal tissues or weirdly placed nerves might fail to absorb the anesthetic, but a large-scale study is still needed. Something tells us not a lot of people with this condition will volunteer to have their nerves exposed and poked at, though.
Cold Urticaria Makes You Allergic To Cold (And Might Kill You)
Being allergic to cold sounds like a total non-sequitur, like being allergic to Belarus' national deficit or attracted to Miles Teller. However, it's a real condition, and it's quite serious. Cold urticaria, or "cold hives," is an allergy to low temperatures in any form. An icy drink, a sudden gust of cold air, or the wrong aisle at the supermarket are all enough to trigger a reaction.
The frosty reception at your next family gathering might be enough to kill you.
The consequences go beyond a mild discomfort: Skin gets hot and irritated, fingers swell up, and it's reportedly quite painful. Getting into a big body of water can trigger pain all over. In some cases, the reaction can even drop your blood pressure and cause trouble breathing. Being constantly on the lookout for peanuts or gluten is bad enough, but at least it's doable -- you can't always ask the waiter if any cold breezes are on the menu tonight.
Cold urticaria can be caused by some infections, but other times there's no discernible reason other than your body suddenly deciding it hates you. The condition is potentially life-threatening if the reaction happens in the wrong area. An icy drink could cut off the airways, or a full-body reaction from a body of water could set off anaphylactic shock. Just being outdoors can be a danger. Then again, so can being indoors if the AC is turned up enough.
"Let's see, keys, phone ... oh, right. Forgot to crawl into a Tauntaun corpse."
Patients with cold urticaria usually need to carry an EpiPen at all times, and take regular medication to ward off the severity of the attacks. Perhaps that's the most painful part of the condition: Cold cannot be avoided, so like The Simpsons, a never-ending series of painful episodes is inevitable.
For more reasons you should never trust yourself ever, check out 5 Things A Body Can Spontaneously Do (Worse Than Combustion) and 5 Mind-Blowing Ways Your Senses Lie to You Every Day.
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