So after he did some murder (of a person and the English language), Minor was committed to the Broadmoor Criminal Lunatic Asylum in 1874. Cut to 1879, when the editor of the yet-to-be-published Oxford English Dictionary put out a call for help. Unlike America's one-volume slapdash effort, the Oxford English Dictionary would use as many volumes as it needed to define every word ever, complete with illustrations and lots of quotes from verifiable sources backing up definitions. Think of the OED as the world's first Wikipedia.

Evening Standard

Minus the personal appeals for money.

Guess who took that request for quotations to his murderous heart? Deep behind the walls of Broadmoor Criminal Insane Asylum, W.C. Minor developed a system of poring through his own library in search of illustrative quotes. So let's say the OED was working on defining the phrase "booty meat." Minor would find a sentence like "The knight's booty meat glistened in the sun" from The Canterbury Tales or whatever. Finding words was all the guy did. For two decades. To the point where he ended up supplying 12,000 illustrative quotes in a two-year span and was the OED's biggest contributor. Each definition was marked with the return address "Broadmoor Asylum," and the editors naturally thought he was a doctor in charge, not an American murderer who'd lost it two decades prior.

Harvey Wiley dropped out of Reasonable Hand Size School.

In 1902, Department of Agriculture chief chemist Harvey Wiley got $5,000 from Congress to figure out what was up with the preservatives getting stuffed into food. Only a few years earlier, soldiers fighting in the Spanish-American War complained that their tinned beef tasted like embalming fluid and smelled like human cadavers -- and they would know, on both counts. Soldiers suspected that the meat was laced with boric acid to hide the fact that it was as putrid as the word "putrid" when you say it like this: "peeeeewtrid."

So Wiley gets his $5,000 and sets up a lab full of chimps to systematically study the effects of eating a diet of food filled with additives. WRONG. He asks a regular crew of volunteers from the Department of Agriculture to ingest poisoned food every day for five years -- just to see what happens. Despite having jobs, salaries, and access to regular not-poisoned food, a dozen otherwise sane men volunteered to eat meals laced with borax, salicylic acid, sulfuric acid, sodium benzoate, and formaldehyde. And the meals were just the beginning of the crazy: Each man also had his poop and pee tested daily to see what was coming out. And each volunteer promised not to hold the government liable, no matter what kind of sludge came out of his tear ducts when he cried himself to sleep at night.

The media ate the story up, every pun intended. Reporters staked out the kitchen to find out what nastiness was on the menu, and a minstrel troupe regularly performed a song called "Song of the Pizen Squad," which was probably the equivalent of getting Konyed at the time.

This is America drinking faulty Chairman Mao juice.

Four years after the experiment began, the Pure Food and Drug Act was passed and the Food and Drug Administration was born. True, other people got on the "What the crap is in our food?" bandwagon in the meantime: Upton Sinclair published The Jungle, and a woman named Alice Lakey spearheaded a national letter-writing campaign to legislate food safety. But the heavy hitter in the fight to regulate food was a guy so crazy that he fed people formaldehyde to prove a point.

Winner of Best White Young Gandhi costume, 1895.

Abraham Flexner was not, repeat, not a doctor. He wasn't even a completer of a post-graduate education. He was an educator who had some innovative ideas about how schools should work, and he published those thoughts in a 1908 book. But he was also kind of belligerent and angry about the subject. He thought lectures were a cheap way to manage a large number of students. American graduates were neither "trained nor serious" workers. Also, where did college entrance exams come from? For real, that was a question he asked in this book. Deans and educators around the country laughed at Flexner's absence of knowledge about higher education. All except for one guy -- the guy who was totally in charge of the Carnegie Foundation, which had been asked by the American Medical Association to totally investigate the nation's medical schools. Dun dun duuuuuuun.

Imagno / Getty

So Abraham Flexner, a non-doctor who wouldn't know what to do with a stethoscope without an Instructable, was sent to judge every medical school in the country. All 155 of them. Guess what? He HATED EVERYTHING he saw. Two-thirds were deemed "utterly hopeless." Chicago's 14 medical schools were described as "a disgrace to the state whose laws permit its existence," "indescribably foul," and "the plague spot of the nation." Flexner recommended shutting down all but 31 of them, including most of the very few schools that admitted women and African-Americans.

The weird part? Everyone did what he said. By 1935, there were only 66 medicals schools left, and most of them were following Flexner's recommendations, which included shutting down the for-profit schools, raising the standards for admittance, and getting students more time in hospitals for practice. The jerky guy who knew nothing about medicine or human communication is actually the reason we don't see complete quacks when we get cancer.

His mustache was into reaching heaven.

If you are a murderer with a time machine, the era right before Lacassagne joined the Forensic Medicine Department of Lyon University is the place to be. Only two things could get you into jail: a forced confession or witnesses who saw you do the deed. Plus, the prevailing theory of the day was that you could spot a criminal by the shape of his forehead and the length of his arms. So if you didn't go around looking like an ape-man, you could probably get away with murder. Lacassagne disagreed. While treating soldiers during military service in Algeria, for example, the doctor decided that tattoos gave insights into the criminal mind -- so he collected and categorized 2,000 images. Can you imagine what he could have done with Instagram? This guy was so into criminals that he actually invented the field of forensic psychiatry, which is basically just the simple idea of asking "Why? Why would someone slit this person's throat and then pee on him?" No one thought to ask the hard question of "why" before Lacassagne.

More importantly, Lacassagne wasn't afraid to look at dead bodies, no matter how horrifyingly disgusting they were. By studying the movement of insects on a dead body, for example, he could figure out how long the deceased had been decaying. He was the first to realize that blood splatter at the scene of the crime could tell you about the victim's injuries. He was the first to figure out that you could totally put a gun or knife in a dead man's hand before the rigor mortis set in, so the old "make it look like suicide" trick wouldn't work on him. He asked criminals to write about themselves from prison so he could study their minds. Then when they died, he LITERALLY studied their minds.

So when authorities finally caught their "French Ripper," Lacassange was asked to analyze him. Was he too insane to go to the guillotine? Nope, said Lacassagne of the terrible, horrible, no good, very bad man. This guy was what we would now call a psychopath, someone who was totally aware of his actions but lacked empathy or remorse. Only they didn't have a word for psychopaths then, because it didn't exist, so he invented it. Standard scientific procedures for autopsies -- all Lacassagne.

Bouncing Balls

Superhero capes? Lacassagne.

Finally, one year before he died, Alexandre LaKickASSange campaigned for an international agency to work on unsolved crimes. And he got it: It's a little agency called Interpol.